Amy A. F. Lutz: The Rise and Fall of the Dexamethasone Suppression Test: Stability, Consensus, Closure.


Jay Amsterdam’s comment on David Healy’s comment


       This is an interesting, if somewhat opining  and peripheral commentary on Dr. Lutz’s posting about the “rise and fall of the DST.” Undoubtedly, most of what Professor Healy writes is correct (in a general sense); however, it has little to do with the DST per se, as the events reported in the Lutz posting took place almost a decade before the introduction of the SSRIs to the marketplace, and more than another decade before the general psychiatric community began to appreciate the fact that these so-called antidepressant compounds were only weakly effective for patients with “melancholic sub-type” of depression.


September 9, 2021